Article source: University of Auckland
Pioneers of needle-free drug delivery have discovered a combination of heat and friction could make many medications smoother and more injectable. This paves the way for new and more highly concentrated drug formulations potentially being able to be delivered needle-free at home.
Currently, many drugs – such as those used in cancer therapy – are made up of large proteins and are thick and gloopy. These are typically thinned down with saline, and the resultant low-concentration, high-volume liquid can only be delivered very slowly through an intravenous infusion in a clinic.
Now a team led by Dr James McKeage and Prof Andrew Taberner (image above) from the Auckland Bioengineering Institute (ABI) at Waipapa Taumata Rau, University of Auckland have found that viscous fluids tend to develop a slippery edge when formed into a high-speed jet; they then become self-lubricating when delivered using a needle-free jet injection.
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